Giovanni Antonio Amato (1475–1555) was an Italian painter of the Renaissance period, active in Naples.
He was also called il Vecchio. He followed the style of Pietro Perugino, and among his pupils were Giovanni Vincenzo Corso, Giovanni Bernardo Lama, Battista Loca, Pietro Negroni, Simone il Giovane Papa, and Cesare Turco. His nephew, Giovanni Antonio di Amato the younger married the painter Mariangiola Criscuolo.